Are you sure it is the Mac? Is it related to resuming from sleep like in this thread? https://forum.fractalaudio.com/threads/axe-fx-3-axe-edit-mac-usb-connection-issue.209037/ Seems there is a correlation for this person with leaving Logic running and the Mac sleeping. I don't leave Logic running when not using it and I don't have an issue. This person resolved it by not letting their disks sleep. I'd opt for not running Logic when not using it personally but to each their own...No specific axe fx drivers sure but there are USB drivers. Either way something is up with the Axe, I would assume its something wrong with this version of the firmware. Hopefully not a hardware issue.