Wood makes a difference. I once ordered 2 telecasters from MF. They both arrived in defective/used condition. They sent 2 replacements. I had all 4 in my possession at once. Same noiseless pickups in all 4. 2 of them were Ash , the other 2 were Alder.
All 4 sounded different , and one (ash) had a tone that was miles above the rest.
It was SO much better sounding , I had my wife listen. She heard it too beyond a doubt.
It was a shame , cause one of the Alder ones had the sweetest neck and was gorgeous. - sounded like ass though. Lol
Unplugged works a little to tell , but for me , a really great clean tube amp will tell you a lot. Dr Z Maz 18 is probably the best one for the job in my arsenal.