Pack the hell out of it, and pack it properly.
When my shiny new Ultra turned up here years ago, it was a box with some form inserts suspending the unit inside the box. That's a good idea, but not enough on it's own IMO. The box had been punctured, and because there were only those little foam inserts inside, whatever it was went straight through to the unit and slightly damaged and shifted the front panel. A stronger box may have helped, but if not it's the same problem. Once something gets through that wall, it's a clear path to the unit inside.
If I were sending an Axe or something similar, I'd take that box (probably fill the space with packing material) and put it inside another bigger box, with the two separated all the way around by a decent layer of good packing material. The heavier the item, the better the packing material needs to be, i.e. shredded paper can be ok for really lightweight items, but for anything with a bit of weight, the weight will crush it down and when it arrives at the other end the contents will have been freely banging about inside in the box.
Anything can be damaged if one tries hard enough (and sometimes it seems they try very hard indeed), but you can certainly do a lot to help protect what's inside. I pack and ship every day as part of my work. At an old job, we used to ship bigger and much heftier rack units across the world (4U DVRs for mass transit). Much stronger boxes, thick custom cut foam inserts, and they were shipped in quantities on pallets. We still occasionally had damaged units. Doesn't really matter how well you've packed something when some moron drives his forks straight into the side of the pallet.