I use the Friedman HBE/BE on many of my presets and I also have the real Amp so I AB them so I can get the closest sound from the original.
I usually set the graphic eq at a medium smily curve starting with the 1khz at 3.5 as the lowest level and move the rest of the freq. 63hz at 0 db,125Hz - 1db, 250Hz -1.5db, 500Hz - 2db , 2 kHz -2db, 4kHz -1db, 8kHz 0db.
These are ballpark figures and it depends on what speaker I use. I use the graphic eq to simulate the Sat switch.
I lower the depth a bit which I believe it simulates the Fat switch on the real amp. My tone controls are set to Bass at 3 or 4, mids at 4, treble at 4 or 5 with the bright switch on and the presence between 2 or 5. The dynamic presence is set at 2 and the gain between 4 to 5. I sometimes use the Sat switch for leads.
I crank the master between 3 to 5 on the HBE and higher on the BE. The sweet spot on my real Friedman is master at 5 depending on what type of power tubes I use . Also the brand of preamp tubes makes a big difference with distorted tones.
I don't use FRFR, I use 3 different Marshall's 4 x 12's and a custom 2 x 12( usually us a 2 x 12 with a 4x 12) and I use Scumback's BM75,H75,M75, Scumnico and S75PVC. For amps I just changed to a Matrix GT1000Fx.