I've found quite the opposite, actually being amazed at how much "better" I think my Axe sounds.
Buddy left his Deluxe Reverb over here last weekend, so naturally I had to plug it in and jam a little, because hey... who can resist any new music gear sitting in their living room, right ? lol
Long story short, sounded good, just like Deluxe's I've owned in the past, and plenty full with the expected "amp in room" because its an amp in the room. But, and this is a but so big Sir Mir A Lot should take notice... I couldn't really get my typical Fender tone I've come to love on the Axe (Big thanks to Mr. Tyler Grund for that). The "Testify" patch, which actually isn't a Deluxe, has that fantastic SRV cranked amp tone, that I really couldn't push the DR to, due to some volume constraints as I live in a condo. Neighbor are pretty cool, but there is a limit.
Likewise, was over another buddies rehearsal space and was jamming on his sweet JVM (really have come to love that amp and if I wanted to still own a Marshall its likely what I'd go for, amazing tones, versatility and bang for the buck) and while its always awesome standing in front of a 1960B cab and feeling that air blowing your pant legs, I really can't stand that type of volume anymore. Rehearsal space is an artist space mostly, converted old warehouse, so kind of poor acoustic, concrete floors, just drywall separating spaces, just was really fatiguing listing to it I found. Didn't want to keep playing.
When I come home to my Axe, I get this great cranked amp tones but at any volume I want. Its not to say it sounds any better than hardware amps, but within the scope I've been able to use real amps anymore, I'm not really able to get the cranked tones I'm after.
Maybe if I dialed in all 6's on the DR, changed out the speaker, and had no concerns about volume it would sound better, but short of doing that, the Axe actually gives me a better tone in my everyday settings.