I haven't tried one in ages, but I sometimes see people that think some are now better (which always makes me laugh, although I don't consider myself a fanboy) and some are pretty awesome (or at least in a mix).
I think you have to make a difference between high gain and others, as even a POD can be close (remembering a quote from Cliff waaaay back, which was of course comparing to earlier Axe firmware too). AFAIK, the genius of Fractal algorithms is more obvious in non-high gain amps.
So if you're talking high gain, it's just a matter of recording the SLO 100 (for example) and trying a demo of the Neural DSP version (as they seem to have the best name?). See if you (or people you trust) can consistently detect or prefer one above the other (if similarly tweaked).
And yes, I trust that Scuffham S-Gear is very good! If I wanted a great one, that's the one I would demo/purchase.