I have to confess, I am a cheapy cable user (always use low/mid priced never hi$). Though I think more expensive cables have a bit less noise, from my experience its barely audible if at all to my ear, so, even using cheap cables throughout my complex music room rig I find it extremely quiet. The tradeoff imo is that my cheap cables will likely fail / begin to fail more often so I have a device to check them if I suspect a problem, but even at that, it's rare I have a failed cable. If you are getting a lot of noise (a lot in imo is enough to drive you crazy as you say) then I'd suggest you either have a failed cable, or, more likely another issue:
- Have you listened through headphones to hear if the noise is still there?
- Have you tried swapping to any other cable to see if anything changes?
- Is the noise there with your guitar volume completely down?