My initial tests were specific to bass guitar, with a GK 1001RBII bass head which is a biamp head, internal crossover at 5k. I would hardly classify this as comprehensive or conclusive in general, since my primary purpose was to simply determine whether these cabinets could satisfy my demands for low-end capacity without pooping out. The results were positive, and didn't sound awful, all things considered. I also tried them with the internal crossover engaged (passive, non-biamp) powered with one side of an old Carver PM350 power amp, running vocals, drum machine (kick drum) and bass guitar (via modeler) through them. They worked....they were loud. Might make a good drum wedge.
My next investigation will be with a Crown xti 4002 power amp, in bi-amp mode, and with the crossover set more realistically for a PA speaker of this type, around 1.2khz-2kz, and with the ability to apply different crossover filter types, compression, and overall EQ to the speaker via Crown's DSP software. In addition, I'm replacing the stock Seismic 15" coaxial with the Ciare NDCX15-2.1 coaxial that I have kicking around from a previous "small box" cabinet I used to use. This should be a significant improvement tonally.
If you were to use these with the Matrix amp, you'd either have to use them with the cabinet's internal crossover, or employ an external crossover and use one channel of the Matrix for lows, one channel for highs, and then wire up a specific cable that would terminate in a Neutrik 4 pin speak-on connector, which is standard for biamp connection via a single connector. Bridge mono, not bi-amped, would guarantee the most headroom, but don't get carried away if you do this as you can fry things.