I have been a MIDI user for a long time, and honestly, I don't know it continues to exist. Yes, it's simple and easy to implement, but if I have to use a physical cable to connect anything, I'd much rather use a communications protocol that is hot-pluggable, supports more complex messages, and can carry higher power to peripherals. My laptop has USB-C, which has some great things going for it, although it means some of my existing peripherals require adaptors.
I am using USB-C for almost everything that is connected via a cable, and I am very satisfied with it. For stage use, I currently connect my AxeFX III to a Mastermind MMGT10 via 7 pin MIDI, which carries power. That requires a cable long enough to reach from the front of the stage to my rack, I have a 30 foot cable. I'd use Faslink via XLR if my MMGT supported it, but alas, it does not. In a better scenario, I would like a reliable wireless comms protocol between my AxeFX and its controller pedal, with a rechargeable battery pack for the board. The messaging protocol doesn't matter, as long as it works. Consider this an official wish list item for Fractal
MIDI 2 includes some interesting enhancements, but I currently can't think of any significant gaps that it needs to fill. If it's designed to extend the base messaging and data exchange capabilities, then perhaps it just becomes a new library for any messaging network. However, my laptop is connected to a monitor, high-speed NAS, digital audio interface, gigabit network, and a dozen peripherals - and has a SINGLE USB-C cable plugged into it, which also provides power to everything other than monitor. The only MIDI cables that I own at this point are my 7 pin cables for my MMGT (a primary cable, and a backup cable). Once someone sorts out the wireless wish list item, it just comes down to choosing between (1) non-powered wireless comms, likely with lower data density, and (2) physical connection that can carry power and high-density comms.
Just my $0.02