Are you referring to the fact that Axe-Edit pauses communication? There’s an option in...
Settings -> Preferences -> Options
“Automatically pause the communication when an Axe-Fx II front-panel change is detected”
If you uncheck that, Axe-Edit will no longer pause communication when changes are detected.
That being said, it’s always been the recommendation to NOT use Axe-Edit and the MFC at the same time, their states are not synced, and you can end up in a situation where you’ve made changes on one that the other is not aware of. The setting to automatically pause was added to alleviate that problem as after you unpause Axe-Edit will rescan the state of the patch and update it’s awareness of the block states properly. It’s not going to cause any damage or major issues, that’s why the option can be disabled, but it can avoid unnecessary confusion, which is why the option was added in the first place.