i just loaded it up. to me, it sounds pretty bad, actually. looking at your cabs, you have linked to a global, so i'm getting the wrong ones - what should they be?
swapping out what i had for something with v30's, it still sounds pretty harsh. if it were me, i'd switch off saturation, put both input gain and overdrive on 7 and put the master on 5. i'd also knock pres back to 2 and put depth on 2 as well
the amp sounds really "hard", if you know what i mean...a little unnatural...i can't tell if you've tweaked any of the advanced params, but i'd be tempted to put them back to default
having said that, putting the petrucci mix ir in sounds a lot better, as it has a lot less high end...so it'll depend entirely on what your cab ir is
all the other fx in the patch seem ok to me.