me personally, mofis connected to headphone jack, mofi amp off, preset properly leveled internally (i.e peaking around the 0.0 line on the OUT1 block level meter), front panel OUT 1 Levels knob a little before noon (i like it at around 47-50% when checked from Setup -> Utilities -> ADC Levels, the mofis can tend to distort on some low frequency content if OUT 1 level is much above 50%). I leave OUTPUT 1 Configuration at default of Mode: Sterdo, Output Level: -10 dBv, Phase: Normal.