What are you using to create your presets (speakers, monitors, headphones), what IEMs are you using? I ran into the same issue when moving from AX8 into an amp to the AX8 direct to the PA. Ended up bringing a laptop to the auditorium and created a couple of presets with the PA system. Took the AX8 home and compared the tones I created at home with what ended up sounding good in the auditorium and discovered my original presets were WAY too bright.
Using in-ears is another can of worms. Unless you're using some good, multi-driver IEMs, your tone is not likely to sound the same as the PA. I would suggest focusing on the PA tone and accept the tone you get in your monitors. Sucks I know, but the main thing is to make sure the audience hears the better tone.
Also, what volume are you using to create your presets? Lower volume (Loud TV) can make "bad" sounding presets sound good. Using studio monitors, I run the volume @ 70 dB (loud for nearfield monitors) to get presets to translate well to most any venue. When using 70 dB, it exposed the brightness of the original presets I created at home.
I actually had to retrain my ears to what a 'good' guitar tone sounds like on my system. I started by just using an amp, AC-20 EF86 Bright, and a corresponding cab, AC-20 DLX MIX. Left everything at the default values and was blown away by how good it sounded and, again, how much brighter the other presets were. Might be worth trying yourself to see if you have the same experience.
