My live setup has evolved to use scenes less frequently, and I opt instead for 1) Song-specific banks for complex songs, which has some issues; and 2) Expression pedals assigned to turn different parts of specific presets on and off or modify groups of effects at once (effectively acting as scene switchers).
So under (1), I have an MFC song with clean, vintage crunch, overdriven rhythm, (1-5 on the bottom row) that I can use for lots of songs; where this is insufficient, I then create song specific banks. The problem of course is the drop during preset switching -- I manage this carefully or use #2 where it's a problem.
Under (2), using a combination of bypass/thru and levels, I can use expression pedals to do lots of things, e.g. one expression pedal to turn the phaser on, boost a drive pedal and add 2 db of volume; or bypass one amp and turn another one. This provides lots of flexibility to do things live and seemlessly.
I am open to suggestions around using scenes more effectively. One issue I have faced is that I find "reveal" mode quite clumsy on the MFC. I have configured reveal IA Switches 4 and 5 to serve as real time preset level changes which comes in handy in new venues; this limits me to 3 scenes per preset which is not enough. Also, when reveal is "on", if I'm not careful, I will inadvertently change a scene (or preset / scene volume!) instead of turning reveal off first and then switching to a new preset.
At some point, I will probably do the hard work to convert everything to scenes, but would love to first find a work around to using switches 4 and 5 for volume adjustments -- that's probably the key obstacle. Maybe I just disable that capability, helpful as it is...
Thoughts welcome -- thanks!