There are various ways to achieve this:
- Engage the "Cut" parameter under the Bass control on the Amp block's Preamp page.
- Use the Various "Low Cut" parameters on the Amp block's Advanced page.
- Use a Filter block.
- Put one of the Tube Screamer style Drive blocks in front of the amp block, Drive at 0.00, Level 10.00 or close to it (my personal favorite way).
- Turn down the Amp block's Drive control/Play with less gain (my personal least favorite way :mrgreen)
If you are using a Drive block before the Amp and it's still a little too "farty", one way I recently tried and really liked was to do a slight bass cut on the Drive's EQ page. I noticed after firmware 10.00 came out that my favorite amp models, the USA Leads (Mesa Mark IV), sounded flubbier than they had before, even with a Drive block in front to tighten them up. After a lot of experimenting, I found that turning down the Bass control on the Drive's EQ page gave me what I was looking for, and without changing the character of the amp like some of the ways I posted above can (IMHO).