You don’t say how loud you are running your rig, but having it loud enough to affect the guitar helps.
I use one or two EV cabs with my Fractals, and run the rig loud enough for the strings to start ringing, just below the point of feedback. When the guitar is reacting to the sound coming from the speaker, and returns it back, is when the guitar and rig comes alive.
It’s not a tweak per se, it’s simply physics in action, and there are some adjustments you can make to approach the situation including sag and speaker compression, but really it’s just volume that matters the most when I’m playing so I leave my settings close to the defaults and enjoy the results. It’s not crazy volume either, it’s just enough for that particular guitar and amp/modeler/speaker to have a conversation.
https://forum.fractalaudio.com/threads/the-modelers-dont-clean-up-with-the-volume-knob-myth.154557/ talks about it that feedback cycle.
PS - This is where IEMs and headphones have a hard time, because they break the acoustic feedback loop. Without that air movement we have to rely on the tweaks, and they can only go so far. Even a small vocal monitor pointed at the guitar and turned up can help make up the difference.