Hear digital noise through usb/firewire powered Audio interfaces, but not Axe FX II, why?

G

Gong8659

Inspired
I have bus-powered M-Audio Firewire solo and Scarlett Solo (3rd gen). Plugged into KRK speakers with 1/4" Jacks.
When operating, I hear digital computer noise, loading software or any PC activity, etc.
Worse on Scarlett, little better on Firewire Solo, but no problem on Axe II.
How can I use the bus-powered Audio interfaces without digital noise?
 
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