State of Epicicity
Fractal Fanatic
Okay, one more idea that has worked for me: set the preamp boost to 0.00 dB, but change the Boost Type from Neutral to another flavor. Mid Boost immediately removes the harshness for me. This is to me a genius part of the Axe FX, the ability to change preamp boost voicings like this; talk about giving your amp the ultimate mod. I understand this is a good way to avoid a drive block, but it does sound different to me; anyway, it's a hell of an effective way to eliminate harshness if you find the right flavor.