The Nitro can become problematic depending on how clean you keep the instrument and your body chemistry plays a role.
This is my biggest concern with Nitro.
Cabinet makers use Lacquer finishes because they dry really fast and in only a couple of hours, they can complete an entire set of cabinets and ship them out the door. I'm sure when Fender and others first starting making guitars, they went to cabinet makers for advice and that's why they used lacquer...not to mention, I don't think poly had been invented yet...don't quote me on that. They probably looked to the automotive industry too, I believe they were using lacquer at the time.
The problem with lacquer however, is it's reaction with body oils and other contaminants. My step-son has very oily skin and when he was living at home, I noticed that after only a few years, the cupboards were getting very sticky around the handles. I did some research and this is when I learned about body chemistry and lacquer reactions. It's why some older nitro guitars get sticky over time. The good thing about nitro, is that it's very forgiving though. You can reapply lacquer over lacquer and the new lacquer will reactivate the old lacquer and the two will basically melt into one another, then cure as one over time. Learning this, I was able to repair the cupboards. So this is one of the cons, ie. oils, etc., about lacquer. One pro though, is that it is forgiving and easy to repair.
I also have a 1987 LPC, which was finished in lacquer and stupid me, I put it on a guitar stand without putting something over the foam padding and it turned the lacquer amber, in a couple of spots. Of course this happened before I had done all the research on lacquer. However, that same LPC, which was arctic white, when it was made, is now a beautiful, warm cream colour. Think Randy Rhoads and Edge's auctioned LPC.