Everyone is different with their specific needs, etc. I have been playing guitar since 1985 and for me, I've always tried to find a balance with price and quality. I've never bought the most expensive gear but also know that going to cheapskate route always results in frustration and getting exactly what you want months later.
I was one of the first to get the Friedman ASM-12 when it came out and went into the purchase completely blind so to speak. I had not heard any clips, read any reviews, etc. other than one. To be honest, I didn't know what to expect because even though one person had a video uploaded, you never know what studio tricks, etc. are being used.
I already had owned a 1x12 Xitone wedge and a Matrix 1x12 cab (the light one). Both were outstanding but as a hard rock/metal guy, there was something in the mids that was too "flat" for my type of tone. I couldn't put my finger on it. I adjusted the EQ, etc. and like I said, sounded great but just wanted to keep searching. I had my eye on the CLR for awhile right when the ASM-12 came out. The ASM-12 was cheaper at the time and nobody had one yet so I was like "what the hell, let's take a chance". I knew that with Friedman quality and expectations, it would at least be decent.
As soon as I plugged into the ASM-12, I felt like I was sitting in front of a guitar cab and instantly I knew I made the right decision. I was smiling and had this "finally!" feeling. Some people want a flatter, more transparent solution and I get that. For me, the Friedman does exactly what I want. With Cliff's adjustments over the past few firmwares, the tones have even got more realistic. I can adust a few things in the CAB block of the Axefx, dip the mids, and it sounds like I'm playng thru a guitar cab.
I still talk about it all the time but really want another Friedman ASM-12 so I can get the full effect. I don't even gig anymore but just thought it would be great to have that setup in my house.
I'd say, take everyone's advice here and there but go with whatever fits your budget, tone needs, etc. I really don't think you can go wrong with any solution. They are all great. Like anything, we all have different tastes in regards to tone.