Yeah, same here sadly.
I actually owned a CAE 3+ SE some years back. Paired it with a VHT 2/50/2 power amp (yes, Lukather fan). I used it on dozens of studio sessions and with dozens of different cabs, with great results. I can’t get the Axe fx model to sound even close, regardless of ir’s or advanced tweaking. I find the model quite boomy, muddy and fizzy, while the real amp was tight, focused an punchy.
My guess is that it’s something I’m not doing right or something I’m not considering, but I don’t want to spend more time figuring out what that is anymore. So I also just moved along.