Drop Axe-Edit before turning off Axe is good practice

If I turn on my Axe 3 after my computer has been on, then audio won't run through the Axe at all until I restart it.
It's done this with two totally different computers now. Windows 10 on both.

That is the only issue I have. If my Focusrite 6i6 is the AI and the AXE3 is off and I power it on... the default AI will switch properly to AXE3... but no sound until a reboot of PC. Disclaimer is that my AXE is on powered hub and I have not had the time to get back to it and get a longer cable to the PC mobo... I never posted about it because I havent done that test but seeing you say it too makes me wonder now. Also Win10 on mine.
 
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