If you're touring or playing in other situations where the venue provides the backline, your pedalboard is your only shot at a consistent sound from night to night. Whatever amp lands in your lap on a given night, just dial it clean and let your pedals work their magic.
This was exactly the reason for me, as I've said before I had a massive G2 (Gigrig) based floorboard, pre-Fractal. Amp (whatever the amp was) was basically all EQs at noon, everything (reverb etc.) from the board.
Means when you show up and your Marshall has somehow become a 70's Princeton, you can cope!