Thank you for all of the suggestions, everyone! I've tired these suggestions, but it still isn't quite there. The boost on the amps works cool, but if I throw something else in front of it, it kinda collapses. It's most noticeable on the neck pickup, but in general gets artifact-ey sounding, where I tend to get a more natural result with real pedals and an amp. While a drive amp into a dirty amp works great, it can't track fast enough with clean amps. Basically trying to simulate edge of breakup amp tones and then turning on one drive for more of that sound, and then another one for more sustain and a good lead sound. Perhaps it's just more experimenting I need. For what it's worth, I feel like the helix did drive pedals really well. If I stacked things, it responded like I expected. With the axe, it seems like I forgot to change the batteries in the drives before a gig if that makes sense haha Just an observation.