I am a cover band player, and I use scenes. There is just no reason not to. With 8 scenes per preset available, you can do anything, with pretty much ultimate power. For me it's not really about dropout or spillover (although... this is a big upside for scenes) but about foot switch management and consistency on how a set works for me.
Consider some of what scenes can do:
1. Up to two amps, two cabs, both with X/Y switching. That's 4 different amps, 4 different cabs you can use in one preset.
2. With scene controllers, you can change things like preamp drive independently for each scene, turning a cleanish or breakup amp into a more driven solo channel. This is like having endless combinations when combined with X/Y. (If you're not familiar with this super powerful feature, learn about it. It's a game changer.)
It makes total sense to me to have one preset per song, and then "scenes" within that song. Some songs use one sound (anything AC/DC comes to mind.) Some have a variety of sound changes. With presets, some songs would need one, and some would need 4 different presets. That makes bank management a nightmare. How do you even label your bottom row for that? I couldn't keep it straight in my head or on my pedal board.
My board is set up with a bank size of zero, and my bottom row is setup to always be scene selection (5 scenes). My scenes are sort of set by song section, but with my own language and twist that works for me. It goes like this: 1. Intro 2. Main 3. Lead 4. Solo 5. Special.
It's kind of a weird setup, I know. I tried doing Intro, verse, chorus, bridge, solo, but I didn't like it. Many songs I do have only one or two sounds. Only a couple make use of the "Special", and frankly I don't really need it, so it's a rare button for me to use. On one sound presets, I can hit any bottom row button, and they are all the same, except scene 4 always has a little volume boost on it for solos.
I personally use the output mixer volume for this. (Many guys use a vol block or a filter. I don't because blocks take CPU, and grid space.) The mixer out can be adjusted with my MFC extension (Vol up Vol down) so if I need to make on the fly adjustments to a solo patch I can. (I do this at practice. Live, that's the FOH guys job). Also, the output mixer is independent for each scene, so you can set different volumes for different scenes. It is very handy for a 4db solo boost, or any other adjustment you need for song parts.