I'm having trouble getting the "in the room" feel and sound from the reverb and delay blocks. This is especially apparent when playing through a PA in a live setting. The reverb, but especially the delay, doesn't sound like it's a natural part of the guitar tone. I would appreciate a few pointers on the general setup of both effects, cause right now I pretty much skip using the altogether.
Here are a couple things to consider.
Are you running a mono or stereo output? If you’re going mono, using delay and reverb (as an effect, not room ambience) in front of the amp will give you more natural results...and make sure you select a mono delay type. The natural decay of the delay block is pretty fast, so you may want to increase the Master Feedback for a smoother trail decay. If you’re using a stereo delay like the 2290, go to the Tone/Duck page and under the Diffusor, select None. That will make it play better with a mono signal
If you’re using a mono signal and want stereo effects, you can put your delay after the cab. It’s not as natural sounding in that it won’t respond with your amp the way it would in front of the amp. Putting it after the amp is like adding delay in post. By itself it can feel a little sterile, but it’s a nice way to get some width if you don’t overuse it.
If you want your reverb to act more like natural ambience, I like putting it at the end of my chain. Try the Recording Studio C type with decay at 0.40 sec, and mix around 8% (if you want it more felt than heard), but play with the mix to where it feels right to you.
One final piece of advice... if you want the Axe to sound like the real thing, you have to treat it like the real thing. If you up your signal chain like you would in the real world, and dial in your amp like you would in the real world, you’ll get familiar results really quickly.