if I switch to a preset with a cab I've saved with de-phase on 4.50, it shouldn't have any latency loading that patch, correct?
i believe that is the lag cliff is speaking of in the first post of this thread.
it seems there still will be some delay or lag when changing the De-Phase parameter (until that gets improved).
so from a performance standpoint, there should be no problem changing Presets/Scenes with different De-Phase settings.