I usually use a preset for a particular sound, and up to 8 scenes.
For example, my Marshall preset is set up for the bottom and top rows. The bottom rows are all base sounds, and the top rows are usually my lead tones based off of my base sounds (like I had set up with my old analog rig). This is how I have my AX8 and my AXE II set up. (On my AXE II, I have more switches to control effects ) I always look at the bottom row as rhythm tones and the top row as lead tones or special effects.
Top row: Lead (+drive +echo +filterboost) Lead (same as left +Chorus) *Special* (depends on patch) Munch Lead
Bottom Row: Crunch Crunch+Chorus+Echo Clean (amp switch) Munch (+Drive)
The special could be anything - lead + Phaser, or Rotory, etc. Depends on the patch. And I only use the Munch lead on my main patch, for other song-specific patches, it could be something different
I made a similar patch using a Rectifier Tones, an identical patch to this with a different clean tone, some special effects for particular songs on the top row, in place of Special and Munch Lead, etc.
I have other song specific patches, that might only have a few scenes, but my lead tone is always the top row, left-most switch. I played that way for over 20 years with my analog rig (ADA MP1, Quadraverb, etc.) so I am real used to the setup.
If I only have a few scenes in a patch, I usually use the extra switches for drive, reverb, delay, other effects, etc.