unix-guy
Master of RTFM
I had (and still have to some degree) a similar issue. When we first started using IEMs, I was not a happy camper.I also prefer IEM over wedges - Using the same Mackie DL32r mixer, I switched from using the headphone output of the Mackie and use line outs (XLR), stereo to the PSM300 and from there to the same in-ear monitors (Shure 535s). The output from the mixer runs close to zero, but it was still easily noticeable that the wireless connection had more noise and less dynamics. It does not sound bad per se, the sound quality is just not as good as the wired connection was.
After similar advice (and more) from @s0c9 and a few others, I spent several hours working on gain staging, adjusting the sensitivity on the transmitter, etc I felt much better.
There is still a degradation in quality from Axe Fx headphone output to DL32R headphone output to Audio Technica transmitter headphone output wireless receiver headphone output. In other words, using the same 6-way 1964 Audio custom molds, I get the best quality straight from the Axe Fx and the worst from the wireless receiver as I move to different points in the chain.
The DL32R headphone output is pretty close to the Axe Fx in sound quality... But not quite the same. Also, I have not retested since moving to the Axe Fx III, which I think has a better headphone output.