just send Out 1 to the FX Loop return. you may want to turn of Power Amp Modeling (most prefer this, but try both ways), and definitely turn off Cab modeling in Setup > Global.
don't turn Out 1 all the way up on the front panel, turn up slowly, as an amp block in a preset can send a lot of signal out of the Axe. you'll have to balance the Out 1 axe volume and the amp's volumes.
or do you want 4 Cable Method AND use amp modeling all at the same time? if so you'll have to have some way to bypass the send to your Amp Instrument Input, since you don't want the real amp running back into the modeled amp.
can you clarify what you want?