Right now I've got the CLRs wired with the sub of this little Klipsch desktop system with the desktop speakers detached. The sub doesn't have an adjustable crossover though so I've had to adjust that with outboard stuff, but for just moderate TV to home theater type volume levels, this setup works great!
My next purchase though will probably be one of the studio subs you can find in the studio monitor section of the big box music stores, if only so I can get a bit more volume when I need it.
Thanks.