The Friedman is a completely different beast than the CLR. Its more than just an eq curve and Its not that it is rolling of high end. There is a lot more than that going on. It feels different too. Between the two you have a different power amp, different drivers, different cabinet and construction and the Friedman is not coaxial like the CLR.
The CLR is a fantastic speaker. To my ears though, it is just too hi fi sounding for stage use. This is of course just my personal opinion based on what I want to hear. I admittedly love the sound of traditional cabs/speakers on staqe at gig volume, and have never bonded with a FRFR monitor trying to reproduce a guitar sound. It's always just "off"". I"m also tired of lugging traditional cabs and power amps around to amplify my AxeFX or AX8 . The Friedman cab fits my needs well, so I use it. That being said, a lot of players like a more full range monitor or at least don't mind it enough to care and are happy with a CLR type of system for gig use. To each there own....If it sounds good. it is good. I now use my CLRs as a second, very loud (LOL) set of studio monitors.
I typically will create my presets on the Adams or the CLRs and then just quick check it on the Friedman. They always translate well. My live presets generally do not have as much highs and/or lows than say, a recording preset, but it isn't drastic.