@Veloso1978 I opened your patch. First thing I noticed is there is a ridiculous amount of gain, even for metal. Turn the gain down on the amp block. Even with the gate block in there, I was feedbacking.
The amp model you're using, the USA IIC++ is known for being a bitch to get a good tone out of. The key with that amp model is to use the GEQ tab on the amp block settings, and make a "smiley face" curve on the EQ. I highly suggest reading Yek's article on this amplifier here:
https://forum.fractalaudio.com/thre...-usa-iic-and-iic-mesa-boogie-mark-iic.115442/
Also, your Marshall 1922 cab has Celestion G12T-75 speakers in it. If you want your FOH tone to be similar to your cab, I would use similar impulses in the Cab block. Right now, your cab block is using a Celestion Greenback (panned 50% left) and a Fender 2x12 Double Verb (panned 50% right). Those are pretty different from your Marshall 1922.
For your cab block, I would try running Stereo Ultra-res factory cab #039, which is a Marshall 4x12 cab with the same speakers as your Marshall 1922, the "T75". I would set both Cab L and Cab R to the same #F039 cab. Make sure those are panned 100% left and 100% right for the full stereo effect.