Years ago I jumped into the FRFR pool and it was not as easy of a decision as I had expected. I think I thought all of the brands would be so similar that it would come down to just price, etc. but I was wrong.
For the record I have only tried an older Matrix cab (NL12) and an older Xitone wedge. I say that because I've heard Xitone have tweaked the options so it is even more FRFR-friendly and I know Matrix has more options now. It is great having so many FRFR options out there but becomes a curse because we all wonder what we are missing out on.
Years ago, I had planned on getting an Atomic CLR cab. Unfortunately they did not have any available at the time so I took a chance on the Friedman ASM-12, which was brand new at the time. I was one of the first guitarists to get one. I absolutely love it and it is perfect for what I do.
I think there are so many things you need to consider and think about. Everyone is different and play different types of music. Also, some people like more mids, less mids, or a light solution for gigs and others might not care at all. The Friedman ASM-12 is probably the heaviest option at 52 lbs but I love mine and doesn't bother me at all. With that said, I don't gig anymore.
I haven't heard a CLR but from what people say, what you put in is exactly what you get out. With the Friedman, it has that sound like you are listening to a guitar cab speaker. I can't explain it any easier or compare because I haven't played a CLR. There are some videos out there where people compare some of the other FRFR solutions and to my ear they are starting to sound similar to each other. That is a good thing I think.
The CLR is more expensive, the Friedman is heavier, the Matrix has so many options, Xitone is tweaking on the fly. I mean, there are even other options out there and I'm sure there are more coming. Ideally would be great if you could hear some in person. One last thing I'll mention is it depends on what type of music you play a bit too. For hard rock and metal, the Friedman sounds phenomenal and that is why I've had mine for awhile and have never wanted anything else. It does palm muting and the metal chug so well. I am sure that every other solution out there has better clean tones than the Friedman.
Good luck!!