Great video. I think the key point the OP makes, which is huge, is you need to learn how mixes, or guitar tones, behave when it's time to translate what you've dialed in from one speaker (and/or environment) to another.
I'm still a relative AX8 newb (about a year in now), but I'm no stranger to the studio, or production etc. I've had better luck using my FRFR (which was only average TBH) to dial in my AX8 sounds. Then I'll check how they sound on my reference monitors, or at a rehearsal etc. When I'm using my reference monitors I'll bring up a jam track, or some tune I'm working on and play along. Which has been helpful for deciding if I've dialed in something too hot or too low in terms of EQ. As I've begun to learn how my sounds translate from one speaker to another it's definitely helped me gain more sonic perspective if that makes sense.
Of course not everyone has multiple speakers, or spaces available to experiment with how tones, or mixes translate from one box, or room to another. But each time I've learned something from it and I think it makes it easier to recognize when you've cut too much of this, or added too much 'that' to your tones.
The latest revelation for me has been getting an older used XiTone active wedge. That's been very enlightening in terms of what a huge difference there really is between a typical PA type FRFR (Alto or QSC in my case) and something like a XiTone. The difference in overall detail is hard to explain, but I love it.