The OP's issue has been solved, but here's a couple of tips for any newbies reading this thread in the future.
RECORDING:
I find that for recording, it's enough to check the sound in studio monitors (check loud, medium and soft volumes), get a second opinion from headphones or other speakers. Any speaker and room will color the sound to some extent, so monitor on different speakers if you can. If you have the time, do this: record the DI (Direct Input) along with your Amp/Cab sound (check the manual, it's easy) and test your mix on various speakers, the car etc. You can re-amp/re-cab the same performance if necessary using the DI.
LIVE:
Set up your live rig and get your sounds. I find testing at gig level is key. The size of the room will be a factor, if you test at home in a small room, it will influence what you hear. You may need to adjust for bigger rooms. Test through a PA if you can. Test at rehearsal with a band. Make changes, take notes, ask your bandmates for opinions. Work on getting a good monitor situation onstage (or with in-ears) and make sure you're sending a good signal to F.O.H.. If you're stereo, check all presets and scenes for phase issues. Be aware that what you're sending to F.O.H. may be quite different than what you hear on your onstage monitor or cab. (If so, check out "Global EQ"). Onstage monitoring: if you're not square in the center of the cone of sound, stick your head in there once in a while and make sure you're not shearing people's ears off with harsh frequencies. On club dates, that's what the first row will mostly hear.
This helped me a lot:
Decide what lower frequencies you can do without. My sound improved a lot when I rolled off some lower frequencies. My FRFR monitor has two high pass options. One at 80 cycles and one at 120. 80 is great for me. You can do this on global EQ, or on the cab block, etc. lots of options. My sounds were clearer without becoming thinner. Perceived volume also increases.
By the same token you can roll off some highs! Try it.
One last tip:
If you're new to the Axe FX, and you're setting up your first gig on it, I highly recommend using as few IRs (Impulse Response = Cabs) as possible. It will help even out your sound from song to song. It will be easier on the sound man.
Good luck!